7. Kirstie Alley
Kirstie Alley gained weight post-menopause, eventually hitting 227 pounds. Between 2005 and 2008, she partnered with the Jenny Craig program, dropped over 66 pounds, and re-established healthy eating habits. “I used to eat whatever I wanted for months,” she said, “but that stopped working.” Her transformation became one of the most publicized weight loss stories of the 2000s.
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